Alpha Lipoic Acid

Alpha-lipoic acid (ALA) is an antioxidant produced by the body that plays a role in mitochondrial energy production. It is both fat- and water-soluble, giving it broader tissue access than most antioxidants. The strongest clinical evidence is in diabetic peripheral neuropathy, multiple RCTs show symptom improvement at 600mg daily IV or oral. Evidence for general antioxidant benefit, glucose metabolism support, and weight loss is more limited and mixed. ALA is generally well-tolerated. The R-form (R-ALA) is the biologically active enantiomer and is considered more potent than the racemic mixture (R/S-ALA) sold in most products. Best supported for those with diabetic neuropathy or metabolic conditions.

Also known as: ALA, Thioctic acid