A searchable database of supplements and lifestyle interventions, rated for research quality, safety, and impact.
Consistent 7-9 hours. The foundation of health. No supplement can compensate for chronic sleep deprivation.
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Antioxidant that supports mitochondrial function and glucose metabolism. Both water and fat soluble.
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Flavonoid from chamomile and parsley. Promotes relaxation and sleep quality. May have anxiolytic and neuroprotective effects.
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Adaptogenic herb. Reduces cortisol and anxiety. Some evidence for strength gains.
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Powerful carotenoid antioxidant from algae. Protects eyes, skin, and mitochondria. Superior antioxidant capacity compared to other carotenoids.
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Comprehensive blend of B vitamins. Supports energy metabolism, nervous system function, and cellular health. Useful for high-stress periods.
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Traditional Ayurvedic herb. Strong evidence for memory enhancement and learning. Effects build over 8-12 weeks.
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Branched-chain amino acids. Popular but largely redundant if protein intake is adequate.
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Natural source of dietary nitrates. Improves blood flow and endurance performance. Effects are acute and dose-dependent.
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Alkaloid from various plants. Powerful blood sugar control comparable to metformin. May cause GI upset initially.
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Amino acid that buffers muscle acidity. Highly effective for high-intensity exercise lasting 1-4 minutes. Causes harmless tingling.
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Rich in anthocyanins that support eye health and circulation. Traditional use for night vision and retinal protection.
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The world's most popular stimulant. Reliable energy and focus boost, but tolerance builds.
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Essential mineral for bone health and muscle function. Most important during growth years and for those at risk of osteoporosis.
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Green algae with potential detoxification properties. Rich in chlorophyll and nutrients. Evidence for heavy metal binding is preliminary.
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Structural component of cartilage. Often paired with glucosamine for joint health. Evidence suggests modest benefits for osteoarthritis.
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Trace mineral that enhances insulin sensitivity. Helpful for blood sugar control and may reduce carb cravings.
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Ceylon cinnamon standardized for polyphenols. Improves insulin sensitivity and blood sugar control. Ceylon variety is safer for long-term use.
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Amino acid that increases nitric oxide production. Improves blood flow and reduces fatigue during exercise.
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Essential for mitochondrial energy production. Levels decline with age. Particularly important if taking statins.
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Deliberate cold exposure via cold showers or ice baths. Builds resilience, may boost metabolism and mood.
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Hydrolyzed collagen that improves skin elasticity, hydration, and reduces wrinkles. Clinically proven to support skin health from within.
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Hydrolyzed collagen protein. Strong evidence for skin elasticity, joint health, and bone density. Types I and III most common.
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One of the most researched supplements. Increases ATP production for muscle and cognitive performance.
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Active compound in turmeric. Powerful anti-inflammatory with extensive research. Needs black pepper or enhanced bioavailability.
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Enhanced absorption curcumin formula with black pepper extract. Superior bioavailability for anti-inflammatory effects.
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Blend of proteases, lipases, and amylases. Aids breakdown of macronutrients and reduces digestive discomfort. Useful for enzyme deficiency.
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Traditional digestive aid with anti-inflammatory properties. Reduces nausea, aids digestion, and may help with joint pain.
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Ancient tree extract used for cognitive support. Improves blood flow to the brain. Mixed evidence for memory in healthy adults.
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Amino sugar that supports cartilage health. Popular for joint pain and osteoarthritis. Effects are modest but consistent.
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Simple amino acid with broad benefits. Improves sleep quality, supports collagen synthesis, and protects liver. Very safe and well-tolerated.
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Glycosaminoglycan that retains moisture. Supports skin hydration, joint lubrication, and tissue repair. Molecular weight affects absorption.
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Time-restricted eating. May improve metabolic health and cellular repair, though largely from calorie restriction.
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Essential for thyroid hormone production and metabolism regulation. Critical for energy and metabolic health. Deficiency is common in areas without iodized salt.
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Essential mineral for oxygen transport and energy production. Critical for those with deficiency, especially women. Test before supplementing.
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Conditionally essential amino acid. Supports intestinal barrier function and gut lining repair. Important during stress or illness.
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Amino acid from tea. Promotes calm focus without sedation. Pairs excellently with caffeine.
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Medicinal mushroom with potential neuroprotective properties. Emerging research on cognitive support.
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Carotenoid that concentrates in the macula. Protects against blue light damage and age-related macular degeneration. Essential for long-term eye health.
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Carotenoids that accumulate in the retina. Strong evidence for protecting against age-related macular degeneration and blue light damage.
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Essential mineral. Supports sleep, muscle function, and stress response. Glycinate form is well-absorbed.
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Mindfulness practice. Solid evidence for stress reduction and focus improvements.
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Natural sleep hormone. Effective for sleep onset, especially with jet lag or shift work.
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Silymarin-rich herb that protects liver cells from toxins and supports liver regeneration. Gold standard for liver health supplementation.
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Powerful hepatoprotective herb. Silymarin protects liver cells and supports regeneration. Extensively studied for liver health.
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Organic sulfur compound. May reduce joint pain and inflammation. Popular among athletes, though research is still emerging.
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Precursor to glutathione, the body's master antioxidant. Supports liver health, cellular detox, and respiratory function.
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NAD+ precursor that declines with age. Emerging research on cellular energy, DNA repair, and longevity. More bioavailable than NR.
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Essential fatty acids from fish oil. Strong evidence for cardiovascular and brain health.
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Essential electrolyte for heart function, blood pressure, and energy metabolism. Most people get enough from fruits and vegetables.
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Cofactor that supports mitochondrial biogenesis. May enhance cellular energy production and cognitive function. Works synergistically with CoQ10.
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Soluble fibers that feed beneficial gut bacteria. Improves microbiome diversity, digestion, and may enhance mineral absorption.
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Beneficial gut bacteria. Emerging evidence for mood support via gut-brain axis. Strain-specific effects vary widely.
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Soluble fiber powerhouse. Exceptional for gut health, regularity, and microbiome support. Also aids cholesterol and blood sugar control.
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Soluble fiber supplement. Excellent for blood sugar control, cholesterol, and digestive health. Very cost-effective.
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Flavonoid antioxidant found in onions and apples. Anti-inflammatory properties with promising longevity research.
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Progressive overload with weights. The single most effective intervention for strength, metabolism, and longevity.
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Polyphenol found in red wine. Activates sirtuins related to longevity, but bioavailability is limited.
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Adaptogenic herb that reduces fatigue and improves stress resilience. Popular among athletes and students.
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Heat stress from sauna bathing. Strong evidence for cardiovascular health and longevity. Finnish studies show impressive benefits.
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Blue-green algae superfood. Rich in protein, vitamins, and antioxidants. May support immune function and reduce inflammation.
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Active compound from broccoli sprouts. Activates antioxidant pathways and supports cellular detoxification. Promising longevity research.
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Conditionally essential amino acid. Supports cardiovascular health, exercise performance, and cellular function. Levels decline with age.
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Fat-soluble vitamin essential for vision, immune function, and cellular health. Deficiency is rare in developed countries.
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Essential vitamin for nerve function and energy metabolism. Critical for vegans. Deficiency causes fatigue and neurological issues.
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Essential antioxidant vitamin. Supports immune function, collagen synthesis, and iron absorption. Most people get enough from diet.
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Essential vitamin that most people are deficient in. Critical for bone health, mood, and immunity.
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Directs calcium to bones and away from arteries. Works synergistically with Vitamin D for bone and cardiovascular health.
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Complete protein source. Convenient way to meet protein targets for muscle building and recovery.
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Essential mineral for immune function and testosterone production. Many people are mildly deficient.
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Low-intensity aerobic exercise where you can maintain a conversation. Builds mitochondrial health and endurance base.
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