Luteolin

Luteolin is a flavonoid found in celery, parsley, chamomile, and many other plants, with potent anti-inflammatory and antioxidant properties demonstrated in cell and animal studies. Human evidence is limited: preliminary research suggests luteolin may support neurological health and reduce inflammation markers, but well-powered RCTs in humans are lacking. Early research suggests it may benefit people with inflammatory conditions or those seeking neuroprotection, though the translational gap between preclinical and human data remains significant. Generally well-tolerated at typical supplemental doses; no major safety signals have emerged in available human studies. PGSS take: Genuinely promising preclinical profile, but honest evidence assessment places it in the 'watch this space' category, the mouse data is exciting, the human data is not yet there.